Cell Therapy

For the First Time, Gene Therapy Delivered Straight to the Lungs

MIT bioengineers advance a technique to deliver nucleic-acid-based treatment to the lung by a noninvasive aerosol inhalation.

Kayt Sukel
February 25, 2019
WEBINAR: Biomanufacturing of Pluripotent Stem Cells and Their Differentiated Progenies in Integrated Bioprocesses

Cell therapy manufacturing is a new discipline where production of adult and pluripotent stem cell types are required for cell therapies. Several hundreds of clinical trials with adult mesenchymal stem cells for therapies such as auto-immune diseases, bone, cartilage repair and stroke are looking promising. For the pluripotent stem cell therapies, retinal pigment epithelial cells, pancreatic islet progenitors and neurons are being applied for treating blindness, diabetes and Parkinson’s disease in early stage clinical trials.

September 10, 2018
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Artificial Lungs Could Offer Real Hope to Future Transplant Patients

The first viable prototype of an artificial lung offers new hope for the more than one thousand people awaiting lung transplants across the United States.

Kayt Sukel
September 04, 2018
Barcoded Nanoparticles Could Optimize Drug Delivery

Barcoded nanoparticles deliver nucleic acids to treat cancer, viral infections, and neurodegenerative diseases.

Melissae Fellet
August 27, 2018
New T-Cell Engineering Process Could Reduce Side Effects

Researchers have improved the ability of cancer-killing T-cells to target pancreatic tumors rather than healthy tissue by engineering the cells to produce more receptors.

Melissae Fellet
August 20, 2018
Blood Stem Cells Grown in Bioreactor May Change Cancer Treatment

For the first time in medical history, a team of researchers has grown and sustained blood stem cells in a bioreactor. The resulting cells could replace painful bone marrow transplants used to produce hematopoietic cells in patients suffering from leukemia and other blood cancers.

Lina Zeldovich
August 13, 2018
Adaptor Cell Could Reverse Fatal Side Effects of CAR T-cell Therapy

Using an intermediate adaptor cell gives clinicians more control over dosage and reverses a potentially fatal side effect of CAR T-cell therapy.

Melissae Fellet
July 20, 2018
Precisely Targeting Tumors with Cancer-Fighting T Cells

Georgia Tech researchers have developed a way to remotely activate the modified T cells from outside the body using a near-infrared laser that very precisely targets cancerous tumors.

Nancy S. Giges
July 09, 2018
A New Sentinel Against Cancer and Other Diseases

Scientists at Harvard’s Wyss Institute for Biologically Inspired Engineering have transformed CRISPR into a powerful mutation surveillance and disease prevention tool.

Michael MacRae
June 18, 2018
Microscope Reveals Subcellular Activity in 3D Living Color

After a decade of work in his lab at the Howard Hughes Medical Institute, Eric Betzig has developed a microscope that presents an unprecedented picture of subcellular activity in 3D living color.

Nancy S. Giges
June 11, 2018
Device Improves Early Detection and Treatment of Cancer

A new device captures circulating tumor cells (CTCs) in the blood stream, providing a new avenue for early detection of metastatic cancer, as well as opportunities to test the source of the cells or the effectiveness of ongoing treatment.

Kayt Sukel
June 04, 2018
Heart-On-A-Chip Achieves Faster Delivery Time

Columbia University researchers recently generated beating cardiac tissue from induced pluripotent stem cells, human cells that are able to differentiate into nearly any cell type. Using physical conditioning, the researchers produced samples with the hallmarks of mature heart tissue with just four weeks of cell culture. The work paves a concrete pathway to functional heart-on-a-chip platforms.

Menaka Wilhelm
May 21, 2018
Simple Solution Supercharges T-Cell Production

Columbia University engineers use a soft mesh scaffold to produce a dramatically higher amount of functional T cells from blood taken from leukemia patients.

Cassie Kelly
May 14, 2018
Podcast: George Church on Portable Genome Monitoring, Aging, and More

Harvard professor George Church discusses advances in portable genome monitoring as well as recent developments in the anti-aging therapies for which is he is so well known.

May 07, 2018