Cell Therapy

Bioprinting Better Artificial Joints

Lorenzo Moroni and his team at University of Maastricht's Institute for Technology-Inspired Regenerative Medicine (MERLN) in The Netherlands, use 3D bioprinting to create "smart scaffolds," which they seed with patient stem cells and growth factors to produce structures that behave like natural cartilage tissues.

Melissa Lutz Blouin
April 30, 2018
Push to Scale Up Cell Therapy Manufacturing

Cellular Biomedicine Group, a clinical-stage biopharmaceutical company that develops immunotherapies for cancer and stem cell therapies for degenerative diseases, recently partnered with GE Healthcare to build a platform to produce therapies at scale for clinical trials. Aims to solve challenge of developing enough genetically modified cells to test products on large populations.

Menaka Wilhelm
April 30, 2018
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Engineering Safety in Cell Therapy

Joseph Wu Director of the Stanford Cardiovascular Institute and Professor of Medicine and Radiology at Stanford University, discusses the rise of engineered cell and tissue products for use in patients. While these products are now technically advanced and better suited for the clinic, there continues to be issues around patient safety that need to be monitored and mitigated for routine use and mass production.

Tanuja Koppal
April 23, 2018
CRISPR Breakthrough Fuels Hope and Fear

For the first time, the revolutionary gene-editing technology called CRISPR-Cas9 was used to repair a disease-causing genetic flaw in viable human embryos and prevent the mutation from being passed to future generations.

Michael MacRae
April 16, 2018
New Drug Program Takes DNA Damage Response Treatment to Next Step

A new nuclease inhibitor drug program could lead to the commercialization of novel DNA damage response (DDR) treatments for female breast, ovarian, and other types of cancers.

Jeff O'Heir
April 09, 2018
Breaking Down Virus Shells to Improve Therapy Deliveries

Rice University researchers have found that breaking down a virus’s tough outer shell creates nanoparticles that could improve the delivery of chemotherapies and other medicines to diseased cells.

John Tibbetts
March 26, 2018
The Challenges and Promise of Cell Therapy Production

Dr. Patrick Hanley, assistant research professor of pediatrics in the Center for Cancer and Immunology research at the Children’s Research Institute in Washington D.C. and director of the Good Manufacturing Practices cell therapy laboratory at Children’s National Health System, on the new developments in the design and manufacturing for T cell therapies. He discussed ways in which technology can help simplify the methodologies and bring consistency and scalability to cell manufacturing.

Tanuja Koppal
March 12, 2018
Engineering Consortium Focuses on Cell Therapy Production

Georgia Tech Engineers created an organization to develop standards and production processes designed to mass produce life-saving cell-based therapeutics at affordable prices. Via AABME.

Nancy S. Giges
March 05, 2018
Doctors Reach for Remote Control to Improve Cancer Care

A new ultrasound technique that manipulates immune cells from outside the body could be the future of cancer care.

Tim Sprinkle
March 05, 2018
Molecular Mailman Improves Delivery of Gene Therapy

Researchers discover new molecular linker that orients targeting antibodies to help nucleic-acid filled particles reach target cells via AABME

Melissae Fellet
February 26, 2018
Scaffold-Grown Tumor Cells to Personalize Cancer Treatments

Testing drugs against patients’ cancer cells—without subjecting patients to chemotherapy—could lead to better, faster treatment.

Menaka Wilhelm
February 12, 2018
Cell Research Taps into Fountain of Youth

A new breakthrough in anti-aging research could lead to gene and stem cell therapies that turn back the hands of time.

Michael MacRae
February 05, 2018
Single-Chamber Bioreactor Grows Both Bone and Cartilage

Researchers at the University of Pittsburgh’s Center for Cellular and Molecular Engineering have developed a small bioreactor that grows constructs of bone and cartilage in a single chamber.

Alan Brown
January 29, 2018
Regenerative Medicine Takes Giant Leaps

Regenerative medicine searches for ways to move into larger tests and commercial products.

Alan Brown
January 22, 2018