WHITE PAPER: Emerging Biomimetic Assays for Cancer Cell Invasion

Cancer cell invasion is associated with systemic metastatic spread throughout the body, resulting in over 9 out of 10 cancer-related fatalities. Most metastatic cancers are carcinomas derived from epithelial tissues such as the skin, prostate, breast, lung, and colon, which typically form sheet-like architectures that line surfaces and cavities. This transition to malignant invasion occurs through the disorganization of tissue architecture and local dissemination through the surrounding extracellular matrix

Cancer cell invasion is associated with systemic metastatic spread throughout the body, resulting in over 9 out of 10 cancer-related fatalities.1 Most metastatic cancers are carcinomas derived from epithelial tissues such as the skin, prostate, breast, lung, and colon, which typically form sheet-like architectures that line surfaces and cavities.2 This transition to malignant invasion occurs through the disorganization of tissue architecture and local dissemination through the surrounding extracellular matrix

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